Sinus Infection: Causes, Treatments, and What You Need to Know

When your sinuses swell and get blocked, you’re dealing with a sinus infection, an inflammation of the sinuses often caused by viruses, bacteria, or allergies. Also known as sinusitis, it’s one of the most common reasons people visit doctors—or just suffer quietly at home. You might feel pressure around your eyes, a stuffy nose, thick mucus, and maybe even a headache or fever. It’s not just a cold that won’t go away—it’s your body fighting off something deeper.

Most sinus infections start with a virus, like the common cold. But if symptoms last more than 10 days or get worse after seeming to improve, bacteria might be to blame. That’s when antibiotics, medications that kill or stop the growth of bacteria come into play. Not every case needs them, but when they do, doxycycline, a broad-spectrum antibiotic often used for respiratory infections and Keflex, a cephalosporin antibiotic effective against many common sinus bacteria are two of the most prescribed options. They’re not interchangeable—your doctor picks based on your history, allergies, and what’s likely causing the infection.

What you won’t find in most guides is how often people confuse sinus infections with allergies or even migraines. The key difference? Allergies usually cause clear mucus and itchy eyes, while infections bring thick yellow or green discharge, pain that worsens when you lean forward, and sometimes a fever. And while over-the-counter decongestants might help you breathe easier, they don’t fix the root problem. If you’ve been on them for days with no relief, it’s time to look deeper.

You’ll also notice that some people try to treat this with supplements or natural remedies. But if you’re dealing with a bacterial infection, those won’t cut it. And mixing them with antibiotics? That can be risky. We’ve seen cases where people took GABA supplements with sedatives and didn’t realize the combo could slow down their breathing. That’s why knowing what you’re taking—and why—isn’t just helpful, it’s necessary.

Below, you’ll find real, no-fluff guides on exactly what works and what doesn’t. From how doxycycline compares to other antibiotics, to when you should call 911 instead of waiting it out, these posts give you the facts without the hype. Whether you’re trying to understand why your doctor picked Keflex over amoxicillin, or you’re worried about antibiotic resistance, you’ll find answers here—straight from people who’ve been there.